new video loaded: Developing Potent Antivirals Is the ‘Direction of the Future’, Fauci Says
Developing Potent Antivirals Is the ‘Direction of the Future’, Fauci Says
Dr. Anthony S. Fauci said on Monday the next phase in the fight against Covid-19 is developing “potent antivirals” that directly act on the SARS-CoV-2 virus.
The bottom line of what we need to do looking forward, and the clear need in this is the development of potent antivirals directly acting on SARS-CoV-2, very similar to what was done with the highly successful drug development program for H.I.V., as well as for Hepatitis C. And what I refer to as the future development of therapeutics will be based on the identification of vulnerable targets in the SARS-CoV-2 replication cycle, and the design of drugs to inhibit these vulnerable targets. As I mentioned, we are beginning this, and this is going to be the direction of the future. Baricitinib and remdesivir have earned emergency use authorization and a number of immunomodulators, including those that block a variety of cytokines and cytokine receptors, are currently in clinical trials. The F.D.A. will give guidance to how these companies can address a problem that we know is with us already, and that will be a problem in the future.